Fungicidal active compound combinations

ABSTRACT

There are described new active compound combinations of a compound of the formula (I) 
     
       
         
         
             
             
         
       
     
     with known fungicidal active compounds, and their use for the control of phytopathogenic fungi.

The present application relates to novel active compound combinationswhich consist of a compound of the formula I

on the one hand and other known fungicidal active compounds on the otherhand and are very highly suitable for the control of phytopathogenicfungi.

It is already known that the compounds of the formula (I) has fungicidalproperties (cf. EP-A 339,418). The activity of this substance is good;however, in some cases it leaves something to be desired at lowapplication rates.

It is also already known that numerous azole derivatives, aromaticcarboxylic acid derivatives, morpholine compounds and other heterocyclescan be employed for the control of fungi (cf. K. H. Büchel“Pflanzenschutz and Schädlingsbekämpfung” [Plant protection and pestcontrol] pages 87, 136, 140, 141 and 146 to 153, Georg Thieme Verlag,Stuttgart 1977).

The action of the substances concerned, however, is not alwayssatisfactory at low application rates.

It has now been found that the new active compound combinations of acompound of the formula I

and(A) dichlofluanid of the formula

and/or(B) tolylfluanid of the formula

and/or(C) tetrachloro-isophthalo-dinitrile of the formula

and/or(D) propineb of the formula

and/or(E) tetramethyl-thiuram disulphide of the formula

and/or(F) mancozeb of the formula

and/or(G) anilazine of the formula

and/or(H) copper oxychlorideand/or(I) captan of the formula

and/or(K) a morpholine derivative of the formula

and/or(L) dithianone of the formula

and/or(M) phaltan of the formula

and/or(N) cymoxanil of the formula

and/or(O) methyl benzimidazole-2-carbamate of the formula

and/or(P) fosetyl of the formula

-   -   or its aluminium adduct        and/or        (O) metalaxyl of the formula

and/or(R) oxadixyl of the formula

and/or(S) fluazinam of the formula

and/or(T)1-(4-chlorophenyl)-4,4-dimethyl-3-(1,2,4-triazol-1-yl-ethyl)-pentan-3-olof the formula

and/or(U) an azole derivative of the formula

and/or(V) an azole derivative from the group consisting ofa) difenconazoleb) penconazolec) flusilazoled) hexaconazolee) myclobutanilf) prochlorazg) fluquinconazoleh) epoxiconazolei) fenpropidinj) perifenoxk)8-t-butyl-2-(N-ethyl-N-n-propylamino)-methyl-1,4-dioxaspiro[4,5]decaneand/or(W) metiramand/or(X) pyrimethaniland/or(Y) diethofencarband/or(Z) mepanipyrim and/or cyprodinyland/or(α) phenylpyrrole and/or(β) iprodioneand/or(Π) vinclozolinand/or(δ) procymidoneand/or(e) benomyland/or(θ) thiphanate and/or

-   -   thiophanate-methyl        and/or        (II) sulphur        and/or        (n) compounds of the formula

have very good fungicidal properties.

The active compound of the formula (I) is known (EP-A-339,418). Thecomponents additionally present in the combinations according to theinvention are also known.

In addition to the active compound of the formula (I), the activecompound combinations according to the invention contain at least oneactive compound from the compounds of the groups (A) to (II). They mayalso moreover contain further fungicidally active admixed components.

If the active compounds are present in the active compound combinationsaccording to the invention in certain weight ratios, the synergisticeffect is seen particularly distinct. However, the weight ratios of theactive compounds in the active compound combinations can be varied witha relatively wide range. In general, the following are proportioned to 1part by weight of active compound of the formula (I)

0.5 to 50 part by weight, preferably 0.5 to 10 parts by weight of activecompound propineb (D) 0.5 to 50 parts by weight, preferaby 0.5 to 10parts by weight of active compound mancozeb (F) 0.5 to 50 parts byweight, preferably 0.5 to 10 parts by weight of active compound TMTD (E)0.5 to 50 parts by weight, preferably 0.5 to 10 parts by weight ofactive compound metiram (W) 0.5 to 50 parts by weight, preferably 0.5 to20 parts by weight of active compound dichlofluanid (A) 0.5 to 50 partsby weight, preferably 0.5 to 20 parts by weight of active compoundtolylfluanid (B) 0.5 to 50 parts by weight, preferably 0.5 to 20 partsby weight of active compound phaltan (M) 0.5 to 50 parts by weight,preferably 0.5 to 50 parts by weight of active compound captan (I) 1 to50 parts by weight, preferably 1 to 20 parts by weight of activecompound Cu oxychloride (H) 1 to 50 parts by weight, preferably 1 to 20parts by weight of active compound sulphur (II) 0.5 to 50 parts byweight, preferably 0.5 to 10 parts by weight of active compoundanilazine (G) 0.5 to 50 parts by weight, preferably 0.5 to 10 parts byweight of active compound chlorothalonil (C) 0.5 to 50 parts by weight,preferably 0.5 to 10 parts by weight of active compound dithianon (L)0.1 to 10 parts by weight, preferably 0.5 to 5 parts by weight of activecompound fluazinam (S) 0.1 to 10 parts by weight, preferably 0.5 to 5parts by weight of active compound pyrimetanil (X) 0.1 to 10 parts byweight, preferably 0.5 to 5 parts by weight of active compounddiethofancarb (Y) 0.1 to 10 parts by weight, preferably 0.5 to 5 partsby weight of active compound mepanipyrin (Z) 0.1 to 10 parts by weight,preferably 0.5 to 5 parts by weight of active compound phenylpyrrole(Saphire) (α) 0.1 20 parts by weight, preferably 0.5 to 10 parts byweight of active compound iprodione (β) 0.1 to 20 parts by weight,preferaby 0.5 to 10 parts by weight of active compound vinclozolin (Υ)0.1 to 20 parts by weight, preferably 0.5 to 10 parts by weight ofactive compound procymidone (δ) 0.1 to 10 parts by weight, preferably0.25 to 5 parts by weight of active compound benomyl (ε) 0.1 to 10 partsby weight, preferably 0.25 to 5 parts by weight of active compoundcarbendazim (o) 0.1 to 10 parts by weight, preferably 0.25 to 5 parts byweight of active compound thiopanate-methyl (Q) 0.1 to 10 parts byweight, preferably 0.25 to 5 parts by weight of active compoundcymoxanil (N) 0.1 to 10 parts by weight, preferably 0.25 to 5 parts byweight of active compound metalaxyl (Q) 0.1 to 10 parts by weight,preferably 0.25 to 5 parts by weight of active compound oxadixyl (R) 0.1to 10 parts by weight, preferably 0.2 to 5 parts by weight of activecompound dimethomorph (K) 0.1 to 20 parts by weight, preferably 0.2 to10 parts by weight of active compound Al fosethyl (P) 0.01 to 10 partsby weight, preferably 0.025 to 5 parts by weight of active compoundtebuconazole (T) 0.01 to 10 parts by weight, preferably 0.025 to 5 partsby weight of active compound triadimefon (U XIXc) 0.01 to 10 parts byweight, preferably 0.025 to 5 parts by weight of active compoundtriadimenol (U XIXa) 0.01 to 10 parts by weight, preferably 0.025 to 5parts by weight of active compound bitertanol (U XIXb) 0.01 to 10 partsby weight, preferably 0.025 to 5 parts by weight of active compounddifenconazole (Va) 0.01 to 10 parts by weight, preferably 0.025 to 5parts by weight of active compound penconazole (Vb) 0.01 to 10 parts byweight, preferably 0.025 to 5 parts by weight of active compoundflueilazole (Vc) 0.01 to 10 parts by weight, preferably 0.025 to 5 partsby weight of active compound hexaconazole (Vd) 0.01 to 10 parts byweight, preferably 0.025 to 5 parts by weight of active compoundmyclobutanil (Ve) 0.01 to 10 parts by weight, preferably 0.025 to 5parts by weight of active compound prochloraz (Vf) 0.01 to 10 parts byweight, preferably 0.025 to 5 parts by weight of active compound offormula ({acute over (η)}a) 0.01 to 10 parts by weight, preferably 0.025to 5 parts by weight of active compound of formula ({acute over (η)}b)

The active compound combinations according to the invention have verygood fungicidal properties and can be employed in particular for thecontrol of phytopathogenic fungi, such as Plasmodiophoromycetes,Oomycetes, Chytridiomycetes, Zygomycetes, Ascomycetes, Basidiomycetes,Deuteromycetes etc.

The active compound combinations according to the invention are veryparticularly suitable for the control of cereal diseases, such asErysiphe, Cochliobolus, Pyrenophora and Leptosphaeria, and againstfungal attack on vegetables, grapes and fruit, for example againstVenturia on apples, Botrytis on beans and Phytophthora on tomatoes.

The good plant tolerability of the active compound combinations in theconcentrations necessary for the control of plant diseases enables atreatment of above-ground parts of plants, of plants and seeds, and ofthe soil.

The active compound combinations according to the invention can beconverted into the customary formulations, such as solutions, emulsions,suspensions, powders, foams, pastes, granules, aerosols, very finecapsules in polymeric substances and in coating compositions for seeds,as well as ULV formulations.

These formulations are produced in a known manner, for example by mixingthe active compounds or the active compound combinations with extenders,that is, liquid solvents, liquefied gases under pressure, and/or solidcarriers, optionally with the use of surface-active agents, that is,emulsifying agents and/or dispersing agents, and/or foam-forming agents.In the case of the use of water as an extender, organic solvents can,for example, also be used as auxiliary solvents. As liquid solvents,there are suitable in the main: aromatics, such as xylene, toluene oralkylnaphthalenes, chlorinated aromatics or chlorinated aliphatichydrocarbons, such as chlorobenzenes, chloroethylenes or methylenechloride, aliphatic hydrocarbons, such as cyclohexane or paraffins, forexample mineral oil fractions, alcohols, such as butanol or glycol aswell as their ethers and esters, ketones, such as acetone, methyl ethylketone, methyl isobutyl ketone or cyclohexanone, strongly polarsolvents, such as dimethylformamide and dimethyl sulphoxide, as well aswater. By liquefied gaseous extenders or carriers are meant liquidswhich are gaseous at ambient temperature and under atmospheric pressure,for example aerosol propellants, such as halogenated hydrocarbons aswell as butane, propane, nitrogen and carbon dioxide. As solid carriersthere are suitable: for example ground natural minerals, such askaolins, clays, talc, chalk, quartz, attapulgite, montmorillonite ordiatomaceous earth, and ground synthetic minerals, such ashighly-disperse silica, alumina and silicates. As solid carriers forgranules there are suitable: for example crushed and fractionatednatural minerals such as calcite, marble, pumice, sepiolite anddolomite, as well as synthetic granules of inorganic and organic meals,and granules of organic material such as sawdust, coconut shells, maizecobs and tobacco stalks. As emulsifying- and/or foam-forming agentsthere are suitable: for example non-ionic and anionic emulsifiers, suchas polyoxyethylene fatty acid esters, polyoxyethylene fatty alcoholethers, for example alkylaryl polyglycol ethers, alkylsulphonates alkylsulphates, arylsulphonates as well as albumen hydrolysis products. Asdispersing agents there are suitable: for example lignin-sulphite wasteliquors and methylcellulose.

Adhesives such as carboxymethylcellulose and natural and syntheticpolymers in the form of powders, granules or latices, such as gumarabic, polyvinyl alcohol and polyvinyl acetate, as well as naturalphospholipids, such as cephalins and lecithins, and syntheticphospholipids, can be used in the formulations. Other additives can bemineral and vegetable oils.

It is possible to use colorants such as inorganic pigments, for exampleiron oxide, titanium oxide and Prussian Blue, and organic dyestuffs,such as alizarin dyestuffs, azo dyestuffs and metal phthalocyaninedyestuffs, and trace nutrients such as salts of iron, manganese, boron,copper, cobalt, molybdenum and zinc.

The formulations in general contain between 0.1 and 95 percent by weightof active compound, preferably between 0.5 and 90%.

The active compound combinations according to the invention can bepresent in the formulations as a mixture with other known activecompounds, such as fungicides, insecticides, acaricides and herbicides,as well as in mixtures with fertilizers or plant growth regulators.

The active compound combinations can be used as such or in the form oftheir formulations or the use forms prepared therefrom, such asready-to-use solutions, emulsifiable concentrates, emulsions,suspensions wettable powders, soluble powders and granules.

They are used in the customary manner, for example by watering,spraying, atomizing, scattering, dusting, brushing on, as a powder fordry seed treatment, as a solution for seed treatment, as a water-solublepowder for seed treatment, as a water-dispersible powder for slurrytreatment, or seed-coating.

In the treatment of parts of plants, the active compound concentrationsin the use forms can be varied within a substantial range. They are, ingeneral, between 1 and 0.0001% by weight, preferably between 0.5 and0.001%.

In the treatment of seed, amounts of active compound of 0.001 to 50 gper kilogram of seed, preferably 0.01 to 10 g, are generally required.

For the treatment of soil, active compound concentrations of 0.00001 to0.1% by weight, preferably 0.0001 to 0.02% by weight, are required atthe site of action.

The good fungicidal action of the active compound combinations accordingto the invention can be seen from the following Examples. While theindividual active compounds have weaknesses in their fungicidal action,the combinations exhibit an action which extends beyond a simpleadditive action.

A synergistic effect is always present with fungicides if the fungicidalaction of the active compound combinations is greater than the sum ofthe actions of the individually applied active compounds.

The action to be expected-for a given combination of two activecompounds can be calculated (cf. Colby, S. R., “Calculating Synergisticand Antagonistic Responses of Herbicide Combinations”, Weeds 15, pages20-22, 1967) as follows:

If

-   X denotes the degree of efficacy, expressed in % of the untreated    control, on use of the active compound A at a concentration of m    ppm,-   Y denotes the degree of efficacy, expressed in % of the untreated    control, on use of the active compound B at a concentration of m    ppm,-   E denotes the expected degree of efficacy, expressed in % of the    untreated control, on use of the active compound A and B at a    concentrations of m and n ppm,

$E = {X + Y - {\frac{X - Y}{100}.}}$

then

If the actual fungicidal action is larger than calculated, thecombination is superadditive in its action, i.e. a synergistic effect ispresent. In this case, the actually observed degree of efficacy must begreater than the value for the expected degree of efficacy (E)calculated from the abovementioned formula:

EXAMPLE 1 Botrytis Test (Bean)/Protective

To produce a suitable preparation of active compound, commerciallyavailable active compound formulations (individual active compounds oractive compound combinations) are diluted with water to the desiredconcentration in each case.

To test for protective activity, young plants are sprayed with thepreparation of active compound until dripping wet. After the spraycoating has dried on, 2 small pieces of agar covered with Botrytiscinerea are placed on each leaf. The inoculated plants are placed in adarkened humid chamber at 20° C.

3 days after the inoculation, the size of the infected spots on theleaves is evaluated.

In order to demonstrate synergism between the active compounds used inthis test, the results were assessed by the method described by Colby(see above).

Active compounds, active compound concentrations and test results can beseen from the following tables.

TABLE 1 Botrytis test (bean)/protective Degree of Active compoundeffectiveness concentration in % of the Active compound in ppm untreatedcontrol

5 51

100 32 Mixture according to the invention $ { \begin{matrix}(I) \\ + \\{Dichlofluanid}\end{matrix}\; \} \begin{matrix}5 \\ + \\100\end{matrix}}\mspace{11mu} \} \mspace{14mu} 89$ Expected value,calculated by the 67 Colby formula (see above)

5 51

50 44 Mixture according to the invention $ { \begin{matrix}(I) \\ + \\{Procymidone}\end{matrix}\; \} \begin{matrix}5 \\ + \\50\end{matrix}}\mspace{11mu} \} \mspace{14mu} 91$ Expected value,calculated by the 73 Colby formula (see above)

5 51

50 0 Mixture according to the invention $ { \begin{matrix}(I) \\ + \\{Phaltan}\end{matrix}\; \} \begin{matrix}5 \\ + \\50\end{matrix}}\mspace{11mu} \} \mspace{14mu} 73$ Expected value,calculated by the 51 Colby formula (see above)

5 51.

5 20 Mixture according to the invention $ { \begin{matrix}(I) \\ + \\{Fluazinam}\end{matrix}\; \} \begin{matrix}5 \\ + \\5\end{matrix}}\mspace{11mu} \} \mspace{14mu} 99$ Expected value,calculated by the 61 Colby formula (see above)

5 51

10 0 Mixture according to the invention $ { \begin{matrix}(I) \\ + \\{Pyrimethanil}\end{matrix}\; \} \begin{matrix}5 \\ + \\10\end{matrix}}\mspace{11mu} \} \mspace{14mu} 93$ Expected value,calculated by the 51 Colby formula (see above)

5 51

5 52 Mixture according to the invention $ { \begin{matrix}(I) \\ + \\{Carbendazim}\end{matrix}\; \} \begin{matrix}5 \\ + \\5\end{matrix}}\mspace{11mu} \} \mspace{14mu} 87$ Expected value,calculated by the 76 Colby formula (see above)

5 51

50 32 Mixture according to the invention $ { \begin{matrix}(I) \\ + \\{Tolylfluanid}\end{matrix}\; \} \begin{matrix}5 \\ + \\50\end{matrix}}\mspace{11mu} \} \mspace{14mu} 84$ Expected value,calculated by the 67 Colby formula (see above)

5 51

200 37 Mixture according to the invention $ { \begin{matrix}(I) \\ + \\{Chlorothalonil}\end{matrix}\; \} \begin{matrix}5 \\ + \\200\end{matrix}}\mspace{11mu} \} \mspace{14mu} 73$ Expected value,calculated by the 69 Colby formula (see above)

EXAMPLE 2 Leptosphaeria nodorum Test (Wheat/Protective

Solvent: 100 parts by weight of dimethylformamideEmulsifier: 0.25 parts by weight of alkylaryl polyglycol ether

To produce a suitable preparation of active compound, 1-part by weightof active compound is mixed with the stated amounts of solvent andemulsifier, and the concentrate is diluted with water to the desiredconcentration.

To test for protective activity, young plants are sprayed with thepreparation of active compound until dew-moist. After the spray coatinghas dried on, the plants are sprayed with a spore suspension ofLeptosphaeria nodorum. The plants remain for 48 hours in an incubationcabin at 20° C. and 100% relative atmospheric humidity.

The plants are placed in a greenhouse at a temperature of 15° C. and arelative atmospheric humidity of about 80%.

Evaluation is effected 10 days after the inoculation.

In this test, a clearly superior activity compared with the prior art isshown, for example, by the compounds according to the followingPreparation Examples:

TABLE 2 Leptosphaeria nodorum test (wheat)/protective Degree of Activecompound effectiveness concentration of the spray in % of the Activecompound liquor in ppm untreated control

25 75

O Tebuconazole + (I) 12.5 + 100 (1:1) 12.5

EXAMPLE 3 Erysiphe Test (Barley)/Protective

Solvent: 10 parts by weight N-methylpyrrolidonEmulsifier: 0.6 parts by weight alkylarylpolyglycolether

To produce a suitable preparation of active compound, 1 part by weightof active compound is mixed with the stated amount of solvent andemulsifier, and the concentrate is diluted with water to the desiredconcentration.

To test for protective activity, young plants are sprayed with thepreparation of active compound until dew-moist. After the spray coatinghas dried on, the plants are dusted with spores of Erysiphe graminis f.sp. hordei.

The plants are placed in a greenhouse at a temperature of about 20° C.and a relative atmospheric humidity of about 80%, in order topromote-the development of powdery mildew pustules.

Evaluation is carried out 7 days after the inoculation.

In this test, a clearly superior activity compared with the prior art isshown, for example, by the compounds according to the followingpreparation examples:

TABLE 3 Erysiphe-Test (barley)/protective Active Degree of compoundeffectiveness concen- in % of the tration untreated Active compound ing/ha control

50 0

50 15

50 85 mixtures according to the invention: (I) + (ηb) 25 + 100 (1.0:1)25 (I) + (ηa) 25 +  58 (1.0:1) 25

EXAMPLE 4 Erysiphe Test (Wheat)/Protective

Solvent: 10 parts by weight N-methylpyrrolidoneEmulsifier: 0.6 parts by weight alkylarylpolyglycolether

To produce a suitable preparation of active compound, 1 part by weightof active compound is mixed with the stated amount of solvent andemulsifier, and the concentrate is diluted with water to the desiredconcentration.

To test for protective activity, young plants are sprayed with spores ofErysiphe graminis f. sp. Hordei. 48 hours after the inoculation, theplants are sprayed with the preparation of active compound untildew-moist.

The plants are placed in a greenhouse at a temperature of about 20° C.and a relative atmospheric humidity of about 80%, in order to promotethe development of powdery mildew pustules.

Evaluation is carried out 7 days after the inoculation.

In this test, a clearly superior activity compared with the prior art isshown, for example, by the compounds according to the followingpreparation examples:

TABLE 4 Erysiphe Test (wheat)/protective Active Degree of compoundeffectiveness concen- in % of the tration untreated Active Compound ing/ha control known:

200 25 8530

200 79

 25 85 mixture according to the invention: (I) + (ηb)  12.5 + 100(1.0:1)  12.5 (I) + (ηa) 100 +  94 (1.0:1) 100

EXAMPLE 5 Erysiphe Test (Wheat)/Protective

Solvent: 10 parts by weight N-methylpyrrolidonEmulsifier: 0.6 parts by weight alkylarylpolyglycolether

To produce a suitable preparation of active compound, 1 part by weightof active compound is mixed with the stated amount of solvent andemulsifier, and the concentrate is diluted with water to the desiredconcentration.

To test for curative activity, young plants are dusted with spores ofErysiphe graminis f. sp. hordei. 48 hours after the inoculation, theplants are sprayed with the preparation of active compound untildew-moist.

The plants are placed in a greenhouse at a temperature of about 20° C.and a relative atmospheric humidity of about 80%, in order to promotethe development of powdery mildew pustules.

Evaluation is carried out 7 days after the inoculation.

In this test, a clearly superior activity compared with the prior art isshown, for example, by the compounds according to the followingpreparation examples:

TABLE 5 Erysiphe-test (wheat)/curative Active Degree of compoundeffectiveness concen- in % of the tration untreated Active compound ing/ha control

200 30

200 75 mixture according to the invention: (I) + (ηa) 100 + 96 (1.0:1)100

EXAMPLE 6 Leptosphaeria nodorum Test (Wheat)/Curative

Solvent: 10 parts by weight of dimethylformamideEmulsifier: 0.6 parts by weight of alkylaryl polyglycol ether

To produce a suitable preparation of active compound 1 part by weight ofactive compound is mixed with the stated amounts of solvent andemulsifier, and the concentrate is diluted with water to the desiredconcentration.

To test for curative activity, young plants are sprayed with thepreparation of active compound until dew-moist. After the spray coatinghas dried on, the plants are sprayed with a spore suspension ofLeptosphaeria nodorum. The plants remain for 48 hours in an incubationcabin at 20° C. and 100% relative atmospheric humidity.

The plants are placed in a greenhouse at a temperature of 15° C. and arelative atmospheric humidity of about 80%.

Evaluation is effected 10 days after the inoculation. In this test, aclearly superior activity compared with the prior art is shown, forexample, by the compounds according to the following PreparationExamples:

TABLE 6 Leptosphaeria nodorum-Test (wheat)/curative Degree of Activeactivity in % compound of the concentration untreated Active compoundsin g/ha control known:

400 25

400 49 mixture according to the invention: (I) + (ηb) 200 + 81 (1.0:1)200

EXAMPLE 7 Pyrenophora teres Test (Barley)/Protective

Solvent: 10 parts by weight of N-methylpyrrolidonEmulsifier: 0.6 parts by weight of alkylaryl polyglycolether

To produce a suitable preparation of active compound, 1 part by weightof active compound is mixed with the stated amounts of solvent andemulsifier, and the concentrate is diluted with water to the desiredconcentration.

To test for protective activity, young plants are sprayed with thepreparation of active compound until dew moist. After the spray coatinghas dried off, the plants are sprayed with a conidia suspension ofPyrenophora teres. The plants then remain in an incubation cabin at 20°C. and 100% relative atmospheric humidity for 48 hours.

The plants are placed in a greenhouse at a temperature of 20° and arelative atmospheric humidity of about 80%.

Evaluation is carried 7 days after the inoculation.

In this test, a clearly superior activity compared with the prior art isshown, for example, by the compounds according to the followingpreparation examples:

TABLE 7 Pyrenophora teres-test (barley)/protective Degree of activeDegree of compound activity in concentration the untreated Activecompound in g/ha control

25 33

25 33 mixture according to the invention: (I) + (ηb) 12.5 + 75 (1.0:1)12.5

1-3. (canceled)
 4. A synergistic fungicidal composition comprisingsynergistic fungicidally effective amounts of the combination of acompound of the formula

and a second compound selected from the group consisting of (D) propinebof the formula

and/or (E) tetramethyl-thiuram disulphide of the formula

and/or (F) mancozeb of the formula

and/or (G) anilazine of the formula

and/or (H) copper oxychloride and/or (K) a morpholine derivative of theformula

and/or (L) dithianone of the formula

and/or (N) cymoxanil of the formula

(P) fosetyl of the formula

or its aluminum adduct and/or (O) metalaxyl of the formula

and/or (R) oxadixyl of the formula

and/or (U) an azole derivative of the formula

and/or (V) an azole derivative from the group consisting of a)difenconazole b) penconazole c) flusilazole d) hexaconazole e)myclobutanil f) prochloraz g) fluquinconazole h) epoxiconazole i)fenpropidin j) perifenox k)8-t-butyl-2-(N-ethyl-N-n-propylamino)-methyl-1,4-dioxaspiro[4,5]decaneand/or (W) metiram and/or (X) diethofencarb and/or (Y) mephanipyrimand/or cyprodinyl and/or (α) phenylpyrrole and/or (β) iprodione and/or(Π) vinclozolin and/or (ε) benomyl and/or (θ) thiphanate and/orthiophanate-methyl and/or (n) compounds of the formula


5. A composition according to claim 4, wherein the weight ratio of thecompound of the formula (I) to active compound of the group (D) isbetween 1:0.5 and 1:50, to active compound of the group (E) is between1:0.5 and 1:50, to active compound of the group (F) is between 1:0.5 and1:50, to active compound of the group (G) is between 1:0.5 and 1:50, toactive compound of the group (H) is between 1:1 and 1:50, to activecompound of the group (K) is between 1:0.1 and 1:10, to active compoundof the group (L) is between 1:0.5 and 1:50, to active compound of thegroup (N) is between 1:0.1 and 1:10, to active compound of the group (P)is between 1:0.1 and 1:20, to active compound of the group (Q) isbetween 1:0.1 and 1:10, to active compound of the group (R) is between1:0.1 and 1:10, to active compound of the group (U) is between 1:0.01and 1:10, to active compound of the group (V) is between 1:0.01 and1:10, to active compound of the group (W) is between 1:0.5 and 1:50, toactive compound of the group (X) is between 1:0.1 and 1:10, to activecompound of the group (Y) is between 1:0.1 and 1:10, to active compoundof the group (α) is between 1:0.1 and 1:10, to active compound of thegroup (β) is between 1:0.1 and 1:20, to active compound of the group (Π)is between 1:0.1 and 1:20, to active compound of the group (ε) isbetween 1:0.1 and 1:10, to active compound of the group (θ) is between1:0.1 and 1:150, to active compound of the group (n) is between 1:0.025and 1:10.
 6. A method of combating fungi which comprises administeringto such fungi or to a fungus habitat a synergistic fungicidallyeffective amount of a composition according to claim
 4. 7. Thesynergistic fungicidal composition according to claim 4, wherein thesecond compound is (β) iprodione or (γ) vinclozolin.
 8. A method ofcombating fungi which comprises administering to such fungi or to afungus habitat a synergistic fungicidally effective amount of acomposition according to claim
 7. 9. The synergistic fungicidalcomposition according to claim 4, wherein the second compound is (α)phenylpyrrole.
 10. A method of combating fungi which comprisesadministering to such fungi or to a fungus habitat a synergisticfungicidally effective amount of a composition according to claim 9.